Eczema on the buttocks can be treated with topical glucocorticoid drugs, glycerite lotion, oral antihistamines (such as loratadine). 1. Topical drugs: for acute eczema without oozing and erosion, glycerite lotion can be used; for acute eczema with oozing and erosion, cold wet compresses can be used with isacridine solution or boric acid solution. For subacute eczema, zinc oxide paste can be used. For chronic eczema, topical glucocorticoid cream can be used, using Dinaid cream, tretinoin cream, halomethasone cream and so on. For those with secondary infection, antibiotic treatment such as fusidic acid cream can be used. 2. Oral medication: If the itching is severe and affects the quality of sleep, antihistamine drugs such as loratadine and diphenhydramine can be taken orally to alleviate the inflammation and stop the itching. Accompanied by a wide range of infections or serious infections, oral amoxicillin, erythromycin and other antibiotic drugs. It is recommended that such eczema patients timely to the hospital, follow the doctor’s instructions for medication, pay attention to local hygiene and cleanliness, wear loose clothing, and avoid sitting for a long time.