The wart will be painful to press may be secondary bacterial infection, specific analysis is as follows: Wart is the common name for warts, mainly the body by the human papilloma virus infection caused by a benign skin epidermal superfluous organisms, with a certain degree of contagiousness, usually does not appear more obvious symptoms, if there is a pain in the pressure, considering the warts by bacterial infection, such as extrusion, picking, scratching lesions, resulting in secondary bacterial infection at the lesions, the symptom of pain in the pressure. Patients can use drugs for anti-infection treatment, such as doxycycline tablets, azithromycin tablets, etc., can effectively relieve the symptoms of pressure pain. The use of the above drugs should strictly follow the doctor’s instructions, it is recommended that patients appear wart pressure pain, timely medical treatment to avoid adverse consequences.