Hepatitis B mothers who give birth to children without immunoglobulin generally do not infect their children with Hepatitis B. This is because Hepatitis B immunoglobulin injections are not generally recommended for mother-to-child blockade (MTCT) in pregnant women with Hepatitis B infection, but rather through immunoglobulin and Hepatitis B vaccine for newborns. Mother-to-child interruption of Hepatitis B is accomplished by immunizing the newborn with a combination of Hepatitis B vaccine and Hepatitis B immunoglobulin as soon as possible within 12 hours of birth, with a second and third dose of Hepatitis B vaccine at 1 month and 6 months of age, respectively, and a blood test for Hepatitis B Pentameter can be brought in at 7 months of age to assess whether interruption has been successful. Generally, mother-to-child transmission of the hepatitis B virus can be reduced to less than 1% when mother-to-child blockade is performed according to the guidelines. However, if the baby is not given the hepatitis B vaccine and hepatitis B immunoglobulin in a timely manner, the risk of the baby being infected by the mother is greatly increased. Mothers with hepatitis B are advised to have their babies vaccinated with hepatitis B vaccine and hepatitis B immunoglobulin in a timely manner after delivery as prescribed by the doctor in order to block mother-to-child transmission of hepatitis B. If the baby has any discomfort after vaccination, he/she should consult a doctor in time.