Penile anesthetic is generally harmless. Penile injection of anesthetic drugs is mainly to prepare for the operation, usually injected in the dorsal side of the penis or around the root of the penis, the purpose is to block the penile nerve pain sensation, to create favorable conditions for the operation, generally no harm to the body, often used for circumcision under local anesthesia. After the anesthetic drug is injected through the root of the penis, it usually takes effect within a few minutes. During the operation, if the anesthetic effect is weakened and pain exists, the anesthetic drug can be injected additionally to ensure the quality of anesthesia and operation; after the operation is over, the local anesthetic drug is metabolized quickly, and there is no adverse effect on the penis and the patient’s body in general. If there are any symptoms of physical discomfort, you should go to the hospital in time and consult your physician for guidance.