Gallstones include gallbladder stones and bile duct stones. In clinical practice, gallstones are usually treated surgically, but preoperative oral medications can also be used to actively fight infection and relieve spasmodic therapy. Common gallbladder stone patients oral drugs are antibiotics, antispasmodic drugs, pain medication. 1. Antibiotics: gallbladder stones or bile duct stones often lead to cholecystitis or cholangitis, antibiotics can be used for anti-infection treatment. Commonly used antibiotics are second-generation or third-generation cephalosporins (e.g. cefuroxime, cefuroxime sodium, cefotaxime sodium, etc.). Can also be combined with other drugs such as quinolones (levofloxacin, etc.), metronidazole, tinidazole and so on. 2. Painkillers: including ibuprofen, acetaminophen tablets, diclofenac sodium enteric-coated tablets and so on. 3. Antispasmodic drugs: when gallstones cause gallbladder spasm, patients may experience abdominal pain, biliary colic and other symptoms. Commonly used antispasmodic drugs are 654-2, Nosipar and so on. 4. choleretic drugs: stone postoperative prophylaxis can be used choleretic drugs, there are goose deoxycholic acid, ursodeoxycholic acid and so on. For patients diagnosed with gallstones, should immediately go to the relevant departments of the regular hospital, under the guidance of a professional physician for treatment, so as not to delay the condition.