Once MS is clearly diagnosed, it should be treated aggressively, mainly to lower blood sugar, control hypertension, diabetes to reduce cardiovascular and cerebrovascular risks and prevent type 2 diabetes. The treatment plan mainly includes general treatment, drugs and surgical treatment. 1, general treatment (1) health education: Currently, many medical personnel focus on diagnosis and treatment, but neglect the education of patients. Health education is the basic measure to prevent and treat MS. Effective education can make patients participate wholeheartedly in treatment and prevention, and reduce patient anxiety, coordinate patients’ understanding of their treatment plan, increase compliance, better control MS risk factors, improve and enhance patients’ quality of life, and reduce cardiovascular-related mortality. (2) Reasonable diet: A reasonable diet structure is important for MS prevention and treatment. Hypertensive patients should strictly control the amount of sodium salt, not more than 6g per day; should control the total calorie intake, while paying attention to the reasonable mix of nutrients (carbohydrates, protein and fat); increase the intake of crude fiber, minerals, plus unsaturated fatty acids, and eat more vegetables and fruits (except for diabetic patients), in order to achieve the purpose of weight loss, lowering blood sugar, lowering blood pressure and regulating blood lipids. (3) Appropriate exercise: Physical exercise guidelines recommend regular, moderate activity, at least 30 minutes a day, long-term adherence can reduce weight, eliminate obesity, lower blood pressure, adjust blood lipids, increase insulin sensitivity, and promote glucose utilization. The appropriate form of exercise can be selected according to the specific situation. (4) Quit smoking and limit alcohol: Smoking can easily cause IR and is an important risk factor for hypertension, etc. All MS patients should quit smoking. Alcohol easily damages the liver and can lead to IR, disorders of glucose and lipid metabolism, and can also raise blood pressure. White wine and beer are harmful to the human body and should be limited with a recommended daily alcohol consumption of <25g for men and <15g for women, while a moderate amount of red wine has vasodilating, anticoagulant and antioxidant effects. (5) Regular life: reduce mental stress and maintain a good state of mind. 2, drug treatment For patients with insignificant effect after general treatment and patients with intermediate and high-risk status of cardiovascular disease, additional drugs should be used for treatment, the purpose of which is to control hypertension, adjust blood lipids, lower blood sugar, etc. (1) Blood pressure lowering therapy: In clear hypertension without diabetes or chronic kidney disease, the target of antihypertensive therapy [66] is blood pressure. If 24-h urinary protein excretion reaches 1 g, blood pressure control should be <125/75 mm Hg. Angiotensin-converting enzyme inhibitors (ACEI) and angiotensin receptor antagonists (ARB), calcium antagonists, β-blockers, and diuretics are often chosen for blood pressure control, and many patients do not achieve their blood pressure targets with a single drug therapy, which can be combined. (2) Correction of dyslipidemia: The lipid regulation target for metabolic syndrome is triglycerides <1.70 mmol/l, HDL-C ≥1.04 mmol/l, and LDL target value depends on the specific situation of the patient. Different drugs or combinations of drugs are used according to the specific conditions of lipid metabolism disorders: statins, fibrates, niacin, bile acid chelators, cholesterol absorption inhibitors, probucol, etc. Clinically, statins are used for hypercholesterolemia, and fibrates are used for hypertriglyceridemia. Inhibitors of hydroxymethylglutarate coenzyme A (HMG-CoA) reductase statins have strong LDL-lowering effects, and can elevate HDL-C with lower triglycerides, reduce IR, and multi-directional effects, such as improving vascular endothelial function, antioxidant effects, inhibiting vascular smooth muscle proliferation, anti-platelet, anti-inflammatory effects occur. Peroxisome proliferator-activated receptor agonists, betablockers, lower triglycerides and elevate HDL-C, thereby reducing cardiovascular disease risk factors in MS patients.