How to treat cerebral white matter degeneration depends on the cause of cerebral white matter degeneration and the severity of the degeneration, as follows: 1, no treatment: If the patient’s cerebral white matter degeneration is mild and does not cause obvious symptoms of neurological deficits, such patients do not need treatment, and only need regular CT, MRI and other imaging examinations. 2, symptomatic treatment: if the degree of cerebral white matter degeneration is very serious, resulting in dementia and other serious neurological deficits, such patients need active treatment. The causes of cerebral white matter degeneration mainly include atherosclerosis, viral infections, autoimmune reactions, etc. Therefore, treatment should be given for these causes, the most common cause being atherosclerosis, and patients need to take anti-atherosclerotic drugs such as aspirin, clopidogrel sulfate tablets, and resulvastatin for treatment. At the same time, treatment should be given for complications such as dementia. The main drugs for dementia include donepezil, memantine hydrochloride, etc.