White spots on the vulva of women do not usually lead to cancer. However, if the white spots grow faster in a short period of time or have serious ulcers that do not heal in a long time, it may lead to cancer. When a woman has white spots on her vulva, she must pay attention to avoid local bacterial and viral infections as much as possible, reduce friction and review regularly. If any abnormality is found, pathological examination should be done in time. If there is a tendency of cancer, surgery is needed for treatment. The occurrence of vulvar leukoplakia in women is related to vulvar malnutrition and may also be related to various factors such as genetics and immunity. The effect of medication is not very obvious. It can be relieved by herbal fumigation or local application of progesterone ointment or testosterone propionate ointment, but it cannot be cured and needs long-term medication.