Recently, I found that many patients have frequent diarrhea, constipation, bloating and abdominal pain, while the colonoscopy report is normal. I think this is gastrointestinal dysfunction. Here I will introduce the symptoms, prevention and treatment of the disease. Gastrointestinal dysfunction has a slow onset and a long duration, with complex symptoms that are continuous or recurrent, and clinical manifestations are dominated by gastrointestinal symptoms. Hiccups, dry mouth, bitter mouth, tightness in the chest, long breath, acid reflux, belching, anorexia, nausea, vomiting, burning sensation under the glabella, fullness after eating, epigastric discomfort or pain, and symptoms worsen with every emotional change. Enteric neurosis, also known as irritable bowel syndrome, is the most common functional disorder of the gastrointestinal tract. Patients often have abdominal pain, bloating, bowel sounds, diarrhea and constipation, left lower abdomen, painful with palpable striated swelling, abdominal pain is often aggravated by eating or cold drinks and relieved after defecation, exhaustion and enema. Abdominal pain is often accompanied by abdominal distension, a feeling of dyspareunia or increased frequency of defecation, and stools can be thin or dry. In the past, this was called colonic dysfunction, colonic spasm, colonic allergy, spastic colitis, mucus colitis, emotional diarrhea, etc. Prevention: First of all, we should pay attention to mental health, lift psychological barriers, adjust the function of the organs; secondly, pay attention to dietary hygiene, when eating must chew slowly, so that food in the mouth to get a full grind cut, and mixed with saliva, to reduce the burden on the stomach, so that food is easier to digest, as little as possible to eat stimulating food, not to mention alcohol and smoking; thirdly, appropriate physical exercise, participate in recreational activities, learn humor can Reduce psychological frustration, seek inner peace, and increase the experience of pleasant life; fourth is to live a regular life, stay up late, do not overexert physical strength, energy, take the initiative to adapt to society and the surrounding environment, pay attention to seasonal climate change and interpersonal relationships and other factors on the body’s adverse effects, to avoid the occurrence or development of gastrointestinal tract dysfunction. Treatment: The treatment of gastrointestinal dysfunction is not about drugs, but about the normal diet and life. Only through mental adjustment and behavior change can we fundamentally adjust the gastrointestinal dysfunction. Traditional treatment is based on diet therapy, nutritional support therapy, sedation and sleep, spasm relief and pain relief, and doctors can use glutamate, digestive enzymes, vitamin B1, gastrodia, morpholine and other treatments according to the symptoms. For patients with obvious psychiatric symptoms, anti-anxiety or antidepressants are given to relieve psychological barriers. It is important to use psychotherapy, whose methods are generally explanation, comfort, guidance, analysis, awareness, positive suggestion and emotional transfer, so that patients can truly understand the condition, actively regulate their emotions, eliminate their ideological concerns and improve their confidence in curing the disease. The key is to obtain a high degree of trust and cooperation from the patient. If necessary, the relevant auxiliary examinations can be suggested to the patient to convince him/her that there is no organic disease, and he/she should have an understanding of the causes of the disease, the nature of the disease and the good prognosis. Next, a variety of effective comprehensive treatments should be administered, including suggestive treatments. General treatment: Unless the patient’s general condition is very poor, he/she does not need bed rest and can participate in moderate amount of labor and work. Life should be regular, often participate in appropriate recreational activities. Diet should be based on less crumbly and easily digestible food, avoiding stimulating diet and strong condiments. Patients with anorexia nervosa must be hospitalized and gradually develop normal eating habits. X-rays, endoscopy, gastric fluid analysis and stool tests should be taken according to different conditions. If necessary, ultrasound and CT examinations should be done to exclude liver, bile, pancreas and other abdominal organ lesions. Severe cases should be treated with medications such as anti-anxiety drugs. They should be taken under the guidance of a doctor.