Loxoprofen Sodium Tablets usually refers to Loxoprofen Sodium Tablets and Ibuprofen usually refers to Ibuprofen Extended-Release Capsules. There are some differences between Loxoprofen Sodium Tablets and Ibuprofen Extended-Release Capsules in terms of composition, efficacy, adverse reactions, contraindications and precautions. 1. Ingredients: The main ingredient of Loxoprofen Sodium Tablets is Loxoprofen Sodium, while the main ingredient of Ibuprofen Extended-Release Capsules is Ibuprofen. 2. Efficacy: Loxoprofen sodium tablets are mainly used for the relief of chronic rheumatoid arthritis, lumbar and leg pain, and frozen shoulder, etc., while ibuprofen extended-release capsules are mainly used for the treatment of fever, rheumatoid arthritis and other diseases caused by pain. 3. Adverse reactions: Loxoprofen sodium tablets can cause shock, acute renal insufficiency, nephrotic syndrome and other adverse reactions. Ibuprofen extended-release capsules may cause gastric bleeding, black stool, stomatitis, tinnitus, blurred vision and other adverse reactions. 4. Contraindications: Loxoprofen sodium tablets are contraindicated in the treatment of perioperative pain in coronary artery bypass graft surgery; severe hepatic and renal impairment. Ibuprofen extended-release capsules are contraindicated in those who are allergic to this product and other antipyretic, analgesic and anti-inflammatory drugs; pregnant and lactating women; active peptic ulcer. 5. Precautions: Loxoprofen sodium tablets should be avoided with other non-steroidal anti-inflammatory drugs, including selective COX-2 inhibitors; when ibuprofen extended-release capsules need to be prohibited when the change in the nature of the drug. It is recommended to follow the doctor’s instructions to standardize the use of Loxoprofen Sodium Tablets and Ibuprofen extended-release capsules, do not blindly use the drug, so as not to cause adverse consequences.