Hepatitis B virus DNA quantification 16 is not serious. Quantitative serum hepatitis B virus DNA testing is used both for the diagnosis of hepatitis B virus infection and as an important indicator of efficacy assessment. The high-sensitivity test can control the normal value of hepatitis B virus DNA detection at 20IU/ml, greater than 20 can appear positive results, lower than 20 indicates that the hepatitis B virus replication ability is reduced, the number of body is small, and the infectiousness is also weak. Serum hepatitis B virus DNA is a direct sign of hepatitis B virus replication and infectiousness. In acute hepatitis B virus infection, serum hepatitis B virus DNA appears earlier; in chronic hepatitis B virus infection, serum hepatitis B virus DNA can be positive continuously. If the result of hepatitis B virus DNA quantitative test is abnormal, it is recommended to consult a doctor in time to identify the cause of the disease and carry out targeted treatment or therapy with the help of a doctor.