1, hepatitis B patients what are the common psychological stress chronic hepatitis B patients’ mental health is a problem that can not be ignored, the pain of the disease itself, the worry about treatment, marriage and family troubles, employment and the economic burden of treatment often bring patients panic, low self-esteem, isolation, resentment and other adverse effects, especially when they just learned the news of their illness, will produce varying degrees of psychological panic, many Patients will be eager to achieve, the phenomenon of blind medical treatment, the wrong medication, the treatment process, bad mentality can aggravate their own condition, psychological stress, their own immunity will be followed by weakening, the disease will aggravate. 2, unwilling to accept the view that hepatitis B is difficult to cure and eager to achieve Based on the existing level of drugs and technology, hepatitis B virus is difficult to be completely cleared, to stop the standard discontinuation of drugs, there are some patients will relapse, the clinical treatment of chronic hepatitis B aims to: long-term suppression of the virus, delay the progress of the disease, improve the quality of life. When patients do not understand the goal of treatment, they usually show an eager mindset, unwilling to long-term treatment, or looking for prescriptions everywhere, always asking the doctor when they can stop the medication, whether they can be cured, suspecting that doctors have a purpose to make themselves adhere to the medication, such a mindset can also bring about psychological deviations, damage family and work relationships, and even be confused by false advertising, making the wrong choice. Therefore, it is recommended that patients take the initiative to learn the correct knowledge of hepatitis B prevention and treatment, understand the controllability, intractability and long-term nature of hepatitis B, adhere to the medication under the guidance of the doctor, review regularly, and keep the liver function at the highest level for a long time. With the current level of medical care, antiviral treatment is actively taken to treat chronic hepatitis B and to effectively prevent the incidence of cirrhosis and hepatocellular liver cancer. The psychological burden, anxiety, and sadness not only do not improve the treatment and turn negative, but also affect the prognosis, so it is better to hold a “come as you are, then rest in peace” attitude, on the one hand, to carry out the necessary treatment, and at the same time to develop good habits of life, and live each day. “The dance of life is not messed up by the hepatitis B virus. 3, hepatitis B treatment does not come in a hurry The patient’s urgent desire for therapeutic effect and the inconsistency of medical hepatitis B treatment goals, in addition to bringing great psychological pressure on patients, will also affect the follow-up treatment, common patient treatment wishes such as: 1, hepatitis B surface antigen (HBsAg) turn negative Hepatitis B surface antigen turn negative often marks the complete eradication of hepatitis B, but the actual situation is limited by the level of technology, even if The conversion rate is very low even when given effective and sufficient courses of antiviral therapy, and cannot be used as a universal goal, so to speak, “hit the jackpot”, for our country, the conversion rate is even lower, because our hepatitis B patients are mostly perinatal or infantile infection, the conversion rate of hepatitis B surface antigen is extremely low. 2, the big three positive to small three positive First of all, we must understand that there is no absolute superiority or inferiority of the two, once turned to small three positive, often means that the viral replication is controlled and the disease remission, indicating that the treatment has an effect, but not this all is well. In fact, the conversion rate is less than 40% for patients treated with interferon, and even lower for patients treated with nucleoside (acid) oral medications under the same course of treatment, so in a short period of time, the simple pursuit of “big three yang” to “small three yang” will often disappoint most people. 3, reduce transaminases Liver-protecting and enzyme-lowering drugs can normalize transaminases, but they cannot inhibit the replication of hepatitis B virus, nor can they stop the progress of the disease, and sometimes they can even cover up the development of the disease, and the transaminases of a few patients have been normal, but the virus in their liver has been in a replication state, and can even develop into cirrhosis. 4, as long as the HBVDNA turns negative can stop treatment Hepatitis B virus amount (HBVDNA is an indicator of the response to hepatitis B virus replication, but also the main basis for judging the efficacy of drugs, some patients soon after the HBVDNA turns negative mistakenly believe that the treatment goal has been reached, they stop treatment, resulting in the loss of efficacy of many patients after stopping drugs, and even aggravation of the disease, and because the patient’s body cccDNA is difficult to Even after the HBVDNA is negative, it is still necessary to adhere to treatment for a longer period of time. Therefore, the correct goal of chronic hepatitis B treatment is to: maximize long-term viral suppression, reduce hepatocyte inflammation and necrosis and liver fibrosis, delay and organize disease progression, reduce and prevent disease progression, reduce and prevent liver decompensation, cirrhosis, liver cancer and its complications, thus improving quality of life and prolonging survival time.