Pain in the middle spine bone of women’s back can be caused by a variety of reasons, physiological reasons such as lumbar muscle strain, and pathologic reasons such as bone spurs, spinal tuberculosis, ankylosing spondylitis and so on. 1. Lumbar muscle strain: If a middle-aged or young woman aged 30 to 50 has recurrent lumbar soreness or distension, and the pain is aggravated by standing or twisting, aggravated by exertion, and relieved by rest or change of position, it is considered to be lumbar muscle strain. 2. Bone spurs: If a middle-aged or elderly woman has spinal bone pain in the middle of the back accompanied by numbness, weakness of the lower limbs, and pain in the lower back and legs, it is considered to be spinal bone spurs. 3. Spinal tuberculosis: If a young woman over 25 years old with family history of tuberculosis has localized pressure or percussion pain in the middle of the back, which is aggravated at night, accompanied by symptoms such as loss of appetite, general malaise, weight loss, indirect fever, etc., it is considered to be spinal tuberculosis. 4. Ankylosing spondylitis: If there is a family history of ankylosing spondylitis, and the pain in the middle of the spine is dull, accompanied by morning stiffness, which is alleviated by activities, ankylosing spondylitis is considered. Women’s spinal pain in the middle of the back can also be seen in other causes, it is recommended to exclude physiological causes of timely visit the hospital to clarify the cause of the disease, timely treatment.