“Rubbing”, “rubbing erythema” or “inter-rubbing rash”, is due to the skin folds of sweat is not easy to evaporate, local wet heat, keratin layer softening, skin rubbing each other, resulting in redness It is an acute inflammatory disease of the skin that causes redness and vesicles. It can be combined with bacterial infection, when the discharge is purulent and smelly; combined with fungal (mainly Candida) infection, the white dip whitening is obvious. Intertriginous rash is most often seen in newborns and obese infants long after birth, where skin insanity and heat are triggering factors. It occurs in the neck, armpits, groin, scrotum and between the thighs. Prevention and treatment methods: pay attention to heat prevention and cooling, infants and children can sleep in air-conditioned rooms. Pay attention to skin hygiene, the skin folds should be washed frequently, keep dry and clean, puff powder can absorb sweat, reduce friction. In the erythematous period with puff powder can be, if there is erosion can be applied zinc oxide oil, tannic acid ointment, combined with infection can be cleaned with 1/5000 potassium permanganate solution, the local use of gentian violet, gentamicin ointment or powder.