Appendicitis pain may be caused by acute or chronic appendicitis, can be treated with antibiotic drugs after diagnosis, but you should go to the hospital in time and follow the doctor’s instructions. 1. Chronic appendicitis: the appendix wall shows different degrees of fibrosis, accompanied by inflammatory cell infiltration. Oral antibiotics, such as ceftazidime, amoxicillin, metronidazole, etc., are needed to carry out anti-infective treatment to eliminate inflammation and then relieve abdominal pain. 2. Acute appendicitis: acute appendicitis is often accompanied by appendicular lumen blockage, or appendicular exudation and suppuration. At this time, the effect of simple oral medication is not obvious, need to cooperate with intravenous rehydration of anti-infective treatment methods, such as ceftriaxone sodium, levofloxacin, metronidazole and other drugs. If there is no improvement, appendectomy is recommended under the guidance of a doctor. As one of the acute abdominal diseases, appendicitis is prohibited to take all kinds of painkillers for pain relief before the diagnosis is confirmed, so as not to mask the symptoms. If the pain of appendicitis persists, please do not self-medicate, it is recommended to go to the hospital for diagnosis and treatment under the guidance of a doctor.