Invasive adenocarcinoma, if there is no distant metastasis, should be treated with surgery, because adenocarcinoma mainly occurs in digestive ducts, but also in breast or liver, pancreas and other parts of the body. For invasive adenocarcinoma of intestines, usually ulcerative lesions are more frequent, and surgery should be chosen early to remove the lesions, and at the same time, anastomosis of the severed ends of intestinal tubes should be performed. After surgery, the choice of adjuvant treatment is based on the detailed pathological stage, the depth of tumor infiltration of the intestinal wall, and the number of lymph node metastases. The most common is intravenous chemotherapy, malignant tumors of the intestinal tract, commonly used chemotherapeutic drugs are oxaliplatin, fluorouracil combined with calcium folinate, because chemotherapeutic drugs have certain toxic side effects, so during the treatment period should be instructed to drink a lot of water, to accelerate the metabolism of drugs.