During menstruation, sleepy eyes can’t be opened mainly because during menstruation, the estrogen and progesterone in the body are decreasing. For example, some people feel particularly tired, depressed, sleepy, and so sleepy that they can’t open their eyes. Others may be irritable and easily lose their temper, and some may also experience insomnia. Therefore, the clinical symptoms caused by the decline of hormone levels vary from individual to individual. Either way, the symptoms are caused by a decrease in hormone levels. Clinically, it can be treated without treatment, but if it has seriously affected the daily life, it is recommended to take oral vitamin B6 and vitamin B1 for regulation.