High prothrombin time generally means prolonged prothrombin time. Prolonged prothrombin time represents a decrease in coagulation factors in the body, which is generally referred to as II, VII, IX, and X. These stable coagulation factors are reduced. What can lead to a decrease in these coagulation factors, generally patients with anticoagulant drugs such as warfarin, can appear prolonged, prothrombin increased, such patients need to be under the guidance of doctors to control the level of coagulation coagulation factors at a reasonable level, so that it does not occur bleeding, but also can play the role of anticoagulation. There are also some people who have not been sick before, but suddenly have prolonged prothrombin time. This is the time to go to the hospital in time to do tests on coagulation function, that is, including tests on coagulation factors, to see which specific factors are lacking. If there is a deficiency of II, VII, IX and X, we should consider whether there is a common condition such as rodenticide poisoning or liver function.