Pimples are clinically known as acne, and the appearance of acne next to the eyebrow is considered to be related to the propagation of Propionibacterium acnes, androgen secretion, or other factors. Acne is a chronic inflammatory skin disease that occurs mainly in the sebaceous gland units of hair follicles, and its etiology is not yet clear. 1. Propionibacterium acnes reproduction: Microorganisms such as Propionibacterium acnes require an anaerobic environment and exuberant oil for reproduction. Sebum can provide a favorable environment, and when sebum secretion is impeded, acne can easily form next to the eyebrows. 2. Excessive secretion of androgens: Androgens can regulate the sebaceous glands of the hair follicles. If there is an imbalance in the level of sex hormones in the body or an increase in the level of androgens, the secretion of the sebaceous glands can increase, and the sebaceous glands can even be enlarged, which can induce acne. 3. Other factors: Acne next to the eyebrow may also be related to abnormal keratinization of the hair follicle, inflammation, heredity, environment and dietary factors. Acne next to the eyebrow should be treated in a timely manner to avoid adverse effects.