The time of growing acne generally has a large individual difference, can be a few months or 1 year to 2 years ranging, or even long-term presence, recurrent episodes, etc.. The phenomenon of acne easily occurs during puberty, which is generally related to the exuberant secretion of sebaceous glands. The duration of acne can vary from a few months to 1~2 years, and the disease can persist for a long time and recur even if the triggers such as staying up late or eating spicy stimuli are not relieved. If acne exists for a long time, standardized treatment should be carried out, and can be treated with retinoic acid drugs, including retinoic acid cream, adapalene gel, and so on. If the surface of the acne is infected, antibiotics can also be used, such as fusidic acid cream. If the acne is serious, you should go to the hospital in time and follow the doctor’s instructions when using the above medications.