Malaria is an insect-borne disease caused by Plasmodium, the source of infection is malaria patients and those with Plasmodium, and the pathogen can be spread through three transmission channels: 1. mosquito bite: it is the main transmission channel, usually female Anopheles mosquitoes, when sucking human blood, its carrying Plasmodium can invade the human body, enter the liver cells and develop and reproduce, then invade the red blood cells The mosquito can enter the liver cells, develop and reproduce, and then invade the red blood cells, causing the rupture of the red blood cells in batches. 2. At present, malaria endemic areas are still mainly located in Africa, Southeast Asia, the Eastern Mediterranean, the Western Pacific and the Americas, etc., with the highest incidence of malaria in sub-Saharan Africa. If you live in or are traveling to areas where malaria is common, you need to take steps to avoid mosquito bites. People who have stayed in malaria-endemic areas during the malaria transmission season, stayed at night or have a history of blood transfusion in the last 2 weeks, and have typical clinical symptoms such as periodic chills, fever, and sweating, need to seek medical attention to clarify whether they have the disease through blood tests. Confirmed malaria does not require isolation and is treated mainly with antimalarial drugs, and most can be cured with timely and aggressive treatment.