Malaria is primarily a mosquito-borne infectious disease and therefore mostly occurs in the summer months. Since mosquito-borne transmission is the most important way of malaria transmission, and malaria is an important mosquito-borne disease, Anopheles mosquitoes are the only vectors of malaria in infected people. Among the fifty-six species of Anopheles mosquitoes known to exist in China, five of them have been shown to be the main vectors for malaria transmission. There are some patients with hypoplasmodemia who have negative blood smear tests, but still may infect the recipient with the disease after blood transfusion. Malaria can also be transmitted through the placenta. Humans are generally susceptible to Plasmodium, and multiple episodes or repeated infections followed by mild or no symptoms of re-infection indicate that a certain level of resistance has developed after infection. In order to cut off the source of infection it is necessary to pay attention to mosquito extermination and prevent being bitten by mosquitoes.