Barrett’s (Barrett’s) esophagus treatments include medications, endoscopic treatments, and surgical procedures, and the methods are constantly updated and refined. Barrett’s esophagus is defined as a lesion in the mucosa of the lower esophagus, in which the complex layer of squamous epithelial cells of the mucosa is replaced by a single layer of columnar epithelial cells. 1. Drug treatment: Proton pump inhibitors (omeprazole) can be chosen to inhibit gastric acid secretion, which can shorten the length of Barrett’s mucosa. Choose prokinetic drugs (domperidone), mucosal protectors (aluminum thioglycollate), etc. to improve the symptoms. 2. Endoscopic treatment: Endoscopic ablation can be performed, and esophageal balloon dilatation can be performed for patients with esophageal stenosis. 3. Surgical treatment: For Barrett’s esophagus with severe reflux, which is not well treated by internal medicine, or with esophageal stricture, refractory ulcer, or severe heterotrophic hyperplasia, surgical treatment can be chosen. Surgical options include Nissen fundoplication and esophagectomy. When Barrett’s esophagus occurs, it is recommended to seek timely medical treatment and standardize the treatment under the guidance of professional doctors. Currently, the treatment programs and guidelines are constantly updated and improved, so you can choose a suitable treatment plan according to your condition.