The time to recovery from neonatal ischemic-hypoxic encephalopathy is related to the severity of the condition and cannot be generalized. Neonatal ischemic-hypoxic encephalopathy is a neonatal hypoxic-ischemic damage to the brain caused by certain factors during the perinatal period. Mild cases of neonatal ischemic-hypoxic encephalopathy are characterized by hyperarousal, excitement, and normal or mildly active primitive reflexes. With aggressive treatment, the symptoms can gradually resolve, usually 72 hours after birth. Moderate cases may show drowsiness, unresponsiveness, reduced muscle tone, and convulsions, which require oxygen, cranial pressure, and anticonvulsant treatment, and can also be gradually relieved. In severe cases of neonatal ischemic-hypoxic encephalopathy, the child will show coma, convulsions, and loss of primitive reflexes, etc. The prognosis is poor and the death rate is high, usually within a few days to a few weeks. In addition, pregnant women should strengthen perinatal monitoring, and if the fetus is moving too frequently or too slowly in utero, they should be checked immediately to avoid intrauterine hypoxia leading to neonatal ischemic-hypoxic encephalopathy.