Toothache headache half face pain is generally caused by wisdom teeth pericoronitis, endodontitis and other diseases, wisdom teeth pericoronitis can be treated locally at the same time as the use of ibuprofen, metronidazole, amoxicillin and other medications, endodontitis medications are ineffective, the need for root canal treatment. 1. Wisdom tooth pericoronitis, if the toothache headache half face pain caused by wisdom tooth pericoronitis, generally can be treated with anti-inflammatory drugs under the guidance of the doctor, such as metronidazole, tinidazole, but also with the use of pain medication, such as ibuprofen, celecoxib and so on. But at the same time, the peri-coronal blind pocket should be rinsed and localized medicine. 2. Pulpitis, some patients with pulpitis after the pulp cavity pressure increases may lead to toothache symptoms, toothache involving the head and face, headache half face pain symptoms, general treatment with drugs is not effective, you can choose to carry out root canal treatment. Usually it is best not to eat spicy stimulating food often, need to maintain a light diet.