Usually, ABO hemolytic jaundice cannot be cured by itself, but it can be cured by active treatment. When jaundice is caused by ABO hemolytic jaundice, it usually cannot be cured by itself, and the patient mostly needs to take treatment measures to improve the uncomfortable symptoms and promote the recovery of the body’s health. ABO hemolytic jaundice can be cured if the patient actively cooperates with the doctor. Clinical treatment for ABO hemolytic jaundice includes glucocorticoids such as prednisolone, dexamethasone and methylprednisolone. Some ABO hemolytic jaundice patients also need to follow the doctor’s instructions with cyclophosphamide, azathioprine, cyclosporine and other immunosuppressants, and 5% sodium bicarbonate alkalinization of urine. For patients with severe conditions, they can also seek medical treatment through allogeneic hematopoietic stem cell transplantation or light therapy, blood exchange therapy. It is recommended that people with clear ABO hemolytic jaundice actively cooperate with doctors for treatment, and pay attention to daily monitoring of the condition, so as to be in a timely manner in the abnormal situation.