It is possible for people who have had kidney to have children. For patients with uremia, kidney transplantation is currently recognized as the best kidney replacement therapy. Kidney transplantation requires long-term, or even lifelong, immunosuppressive drugs, and if the drugs have an effect on male sperm quality, male fertility will certainly be affected accordingly. For female patients of childbearing age, pregnancy is possible and the survival rate of newborns is high, but during pregnancy, the risk of infection and diabetes is high due to the use of hormones and immunosuppressants, which should be closely observed. It is recommended that pregnancy should be carried out 1-2 years after transplantation, with normal and stable renal function and low dosage of immunosuppressive drugs. During pregnancy, you must monitor your own kidney function in real time, go to a hospital with advantageous medical resources for pregnancy checkup regularly, if there is any danger, you should seek medical attention in time, protect the safety of adults and children as much as possible, low salt and low fat diet, quit smoking and alcohol to ensure the health of the transplanted kidney.