Asthma persistent state should choose glucocorticoids to control, glucocorticoids can act on airway inflammation formation relief, inhibit the aggregation of eosinophils, control the release of inflammatory mediators. Increase the responsiveness of airway smooth muscle to β2 receptors to dilate the bronchial tubes, the drug is mainly divided into inhalation, oral and intravenous drugs, inhaled glucocorticosteroids are mainly beclomethasone, budesonide, fluticasone. Oral can choose prednisone, prednisolone, severe asthma and severe attacks should be given early intravenous use of drugs. After the asthma control, we should pay attention to the life to strengthen physical exercise, enhance physical fitness and avoid contact with allergens.