White pustules on newborns are medically called neonatal impetigo. Neonatal impetigo is mainly a skin infection caused by bacteria, the common bacteria is Staphylococcus aureus. It is important to pay attention to hygiene, keep the skin clean to avoid infection, and wash your hands before touching your newborn. For mild neonatal impetigo, pay attention to skin care and use topical Bactrim 2-3 times a day, the symptoms will improve significantly after 2-3 days of medication. If the white pustules are larger in extent and have fused into patches, hospitalization is recommended to enhance skin care, apply intravenous antibiotics, and incise the pustules if necessary.