Unexplained pain in the roots of the fingers is not very much related to emphysema. Emphysema is an abnormal and persistent dilatation of the distal air spaces of the terminal bronchi of the lungs, accompanied by destruction of the alveoli and bronchi, without significant pulmonary fibrosis. The main symptoms caused by this disease are coughing, coughing up sputum, and chest tightness and shortness of breath or dyspnea after activity. Emphysema can cause pestle finger, which manifests itself as an enlarged pestle-like bulge at the end of the fingers or toes, but usually does not cause pain. There are various reasons for unexplained pain at the root of the finger, such as accidental contusion or impact to the root of the finger, where the ligament and joint capsule are damaged. Rheumatic diseases, such as rheumatoid arthritis, may also cause finger pain. Unexplained pain in the root of the finger can be caused by a variety of reasons, it is recommended to consult a doctor in a timely manner, complete the examination, identify the specific causes, and follow the doctor’s instructions for treatment.