With a high risk of Down’s Screening for Trisomy 21-Trisomy, if the amniocentesis test results are normal, the child is usually wanted; conversely, the child is not wanted. Down’s syndrome screening is done by drawing blood to check the serum levels of alpha-fetoprotein, human chorionic gonadotropin, and free estriol of a pregnant woman, and then combining it with the woman’s age, weight, and gestational week to determine the risk of the fetus developing 21-trisomy syndrome. If the Down’s syndrome test reveals a high risk, amniocentesis is required. If the amniocentesis test results are normal, the pregnancy can continue. If the result of amniocentesis test is abnormal, it means the fetus has trisomy 21 or other chromosomal abnormalities, and it is recommended to terminate the pregnancy to avoid the birth of malformed babies. It is recommended that pregnant women pay attention to regular checkups during pregnancy, and once fetal abnormalities are detected, it is recommended that they consult a doctor in a timely manner, and under the guidance of the doctor, complete the relevant examinations to clarify the cause of the disease and treat the symptoms.