Lobular hemorrhage under the finger and toe nails is one of the signs of infective endocarditis. Infective endocarditis (IE) is a direct infection by microorganisms (bacteria, fungi and other microorganisms such as viruses, rickettsia, chlamydia, spirochetes, etc.) that produce inflammation of the endocardium of the heart valves or ventricular wall, including acute and subacute endocarditis. What should be done to prevent and treat subacinar hemorrhage in finger and toe nails? The following is a brief introduction: 1. Patients with susceptibility factors should be given measures to prevent infection when doing surgery or operations. (1) For oral and upper respiratory tract operations or surgeries, antibiotics against Streptococcus griseus should be given. (2) urinary, reproductive and digestive system surgery or operation, should be given for enterococci. 2.Antibiotic treatment: This is the most important treatment measure. (1) empirical treatment: when the pathogenic microorganism has not yet been cultured using ① acute SIE with nafcillin injection or drip, plus ampicillin injection or drip, or add gentamicin; ② subacute people in accordance with the common pathogenic streptococcus, the choice of penicillin-based (3.2 million to 4 million U, every 4-6 hours), plus gentamicin. Once the causative organism is identified, it should be adjusted accordingly according to the drug sensitivity test.