Sleep and wakefulness are advanced activities of human beings, and sleep accounts for one third of life, during which the organs of the organism get rest and physical fitness is restored. If long-term sleep deprivation will seriously affect the function of the brain and organs, may cause the following diseases: 1, mental disorders: adequate sleep time can make people’s physical and mental energy fully recovered, keep the brain clear, if long-term sleep deprivation will make the brain does not get normal rest, will lead to brain cell ischemia and hypoxia, appear slow reaction, memory loss and other performance, serious cases will occur Depression, anxiety and plant nerve dysfunction, and even lead to mental disorders. 2, endocrine: sleep state on the internal part of the impact is particularly obvious, good sleep is closely related to the normal rhythm of the body, long-term sleep deprivation will disrupt the body’s biological clock, resulting in hormone secretion disorders, inducing endocrine disorders; 3, aggravate the original disease: normal sleep can maintain the normal immune function of the body cells, if long-term sleep deprivation, will make the immune system decline, thus aggravating the original disease, especially common If you do not have enough sleep for a long time, the immunity will be reduced, thus aggravating the original diseases, especially the common hypertension, cardiovascular diseases, sleep deprivation and the original diseases affect each other, forming a vicious circle. 4, the impact on special groups: long-term sleep deprivation makes many women’s face dull, dull skin, dryness, increased pigmentation and wrinkles. Insomnia has become the main enemy of modern women’s health and beauty. It will also accelerate the aging process of women, leading to early menopause; will lead to shortened life expectancy of the elderly, dementia, neurasthenia, etc.; will also seriously affect the growth and development of adolescents, affecting brain function to reduce learning efficiency. 5, insomnia will make the body immune system: the resistance to disease is weakened, easy to cause disease. In summary, long-term sleep deprivation not only seriously affects the normal life and work of humans, but also has a great danger to human health, need to pay attention to and timely conditioning.