Adrenal masses include two major categories: functional adenomas and cortical carcinomas, nonfunctional benign tumors, and malignant carcinomas, with as many as dozens of types detailed. With recent advances in examination techniques, morphological changes in the adrenal gland can be detected earlier, even in masses <1 cm (diameter), changing the previous diagnostic procedure of searching for the presence of tumors in the adrenal gland when characteristic clinical symptoms were caused by abnormal hormone secretion. When adrenal masses are detected, first of all, attention should be paid to whether they are accompanied by clinical symptoms of excessive secretion of certain adrenal hormones, such as hypertension and hypokalemia caused by excessive secretion of salt corticosteroids (aldosterone); centripetal obesity, hypertension and polycythemia caused by excessive secretion of glucocorticoids; female masculinity, hirsutism or male feminization caused by excessive secretion of sex hormones; hypertension, hyperhidrosis and paroxysmal palpitations caused by excessive secretion of medullary catecholamines. excessive sweating and paroxysmal palpitations. The corresponding hormone levels should be checked. As long as there are signs of abnormal hormone secretion and confirmed by laboratory tests, regardless of the size of the detected adrenal mass and whether it is malignant or not, surgery should be performed as soon as possible in order to reduce the damage caused by excessive hormone secretion.