The main difference between nucleic acid testing and antigen testing is that: nucleic acid testing is more accurate and is the basis for confirming the diagnosis, but the means of detection is complicated; antigen testing is simpler, but less sensitive. 1. Nucleic acid test: identifies the nucleic acid of the virus, i.e. genetic material, and detects it by amplifying the nucleic acid, with high sensitivity and specificity, which is the basis for confirming the diagnosis of viral infection. Nucleic acid test needs to be sampled and tested by professional testing personnel, and the cost is high and the result is slow. 2. Antigen detection: identify the antigen of the virus, i.e. the protein wrapped outside the genetic material of the virus, and identify it through antigen-antibody binding, with low sensitivity and specificity, which cannot be used as the basis for confirming the diagnosis of viral infection. The antigen test can be self-operated, with lower cost and quicker result time. It is suitable for people under quarantine observation, people with fever and other symptoms, and residents who need antigen testing. Note: Antigen test cannot replace nucleic acid test.