I. After starting treatment for schizophrenia, the clinical manifestations faced are mainly the following: 1. positive symptoms: mainly including hallucinations, delusions, impulsive behavior, etc.; 2. negative symptoms: mainly including poor thinking, emotional indifference, lack of will; 3. impaired emotion: dull expression, no affection with family, etc.; 4. impaired self-awareness: not knowing that their abnormal performance is pathological and refusing to seek medical treatment and medication; 5. 5, cognitive impairment: mainly includes memory, attention, executive function (simply understood as decision-making ability), verbal fluency, etc.; 6, impaired social function: in mild cases, the original ability to learn and work is impaired, and in severe cases, the ability to take care of oneself in life (such as the ability to actively eat, wash, change clothes, etc.) is lost; 7, the inevitable side effects of drug treatment. Second, the time required for the elimination of different clinical manifestations is different: 1. Positive symptoms: within six months and one year after the first onset of the disease, in the case of sensitivity to drugs, will generally gradually disappear within half a month and two months after the drugs are added to the treatment amount. The relevant predictors are 1) acute onset; 2) short duration of illness; 3) no previous history of psychiatric illness; 4) having active affective symptoms; 5) older age of onset; 6) good pre-morbid personality; 7) good social adjustment; 8) good social interactions; and 9) excellent work performance but time of onset. Positive symptoms with the following factors are likely to fail to eliminate or even remain, including: 1) slow onset; 2) long duration of illness; 3) history of mental illness; 4) emotional indifference; 5) young age of onset; 6) pre-morbid personality abnormalities; 7) poor social adjustment; 8) tendency to social isolation; and 9) poor work performance. About 60% of patients who relapse again are not as sensitive to antipsychotic drugs as they were the first time. While first-episode antipsychotics with smaller doses and fewer side effects are effective for about a month, relapsing patients may be ineffective with larger doses of the first antipsychotic. Even if it is effective, the time for the relapse treatment to take effect will be significantly longer than the first treatment, which may be two months, six months, one year, or even two years. This is why families often ask doctors, “Why is my child so effective the first time, but not the second time?” Therefore, I often tell families that the treatment for patients with relapses is “time for space” and “time for efficacy”. For patients who have relapsed again, if your current treatment is the strongest and highest dose treatment plan that can be chosen by experienced doctors according to the patient’s symptoms, all parents can do is to wait patiently. This is also the reason why I have repeatedly urged the family never to reduce and stop the medication to make the disease relapse. But what makes doctors speechless is that 80% of parents ignore their doctors’ painful words. 2, negative symptoms: negative symptoms are divided into primary negative symptoms and secondary negative symptoms. The overall efficacy of current antipsychotics for primary negative symptoms is not good, and generally only about 60% improvement after a long time of medication, so overall primary negative symptoms cannot be cured. Negative symptoms secondary to positive symptoms will gradually disappear within 3 months to 6 months after the disappearance of positive symptoms; negative symptoms secondary to drug side effects, such as extrapyramidal reactions (tremor, rigidity, etc.), can be relieved within 1 month after the disappearance of drug side effects.3. Emotional impairment: Emotional impairment is actually a negative symptom, and the recovery time can be referred to negative symptoms. But the reason why it is listed separately is that many parents are anxious and impatient for the recovery of emotion.4. Impaired self-knowledge: It takes 3 months to 6 months for the real recovery of self-knowledge, and some patients even need 1 year to 6 months.5. Cognitive impairment: There will be about 30% of patients who will gradually recover within 6 months after the disappearance of positive symptoms, which is the reason why it usually takes at least 6 years for students to recover to school level after getting the disease. This is why it usually takes at least six months for students to return to school, and it is useless for parents to be anxious; about 70% of patients do not recover their cognitive function to the pre-morbid level. At present, there is no western medicine that can effectively improve the cognitive impairment of schizophrenia, and this is the reason why our group carries out Chinese medicine to treat the cognitive impairment of schizophrenia.6. Impaired social function: Since the recovery of social function is closely related to the recovery of cognitive function, and only about 30% of patients’ cognitive function will generally recover gradually within 6 months after the disappearance of positive symptoms, only about 30% of Therefore, only about 30% of patients can recover to the level of completing complex learning and work tasks, i.e., only about 30% of patients can be socially competitive after treatment. 50% of about 70% of patients can recover to the level of completing simple learning and work tasks, and the other 50% cannot recover to the level of completing simple learning and work tasks, including even simple self-care.7. Inevitable side effects of drug treatment Side effects: A variety of more or less side effects are inevitable in the course of schizophrenia treatment, and it is an impossible task for most people at present to hope for both a cure and no side effects, but most drug side effects are gradually tolerated and disappear. Parents should not choke on their children’s medication, or use enough medication, or pick and choose the medication like a lesbian picking clothes, constantly changing the medication, the condition is slightly better that the solution or stop medication, resulting in the child missed the best treatment period, the condition relapses into chronic, intractable. Common and drug side effects and the disappearance of time is roughly as follows: 1) sleepiness, drowsiness: generally 3 months to 6 months after the drug gradually tolerated disappearance, some people need 1 year to 3 years; 2) extrapyramidal reactions (tremor, stiffness, etc.): tremor, stiffness generally 3 months to 6 months after the drug gradually tolerated disappearance, some people need 1 year; but late-onset dyskinesia will be irreversible if the drug is not changed; 3) Weight gain: generally in the first six months of the drug, generally increased by 5 pounds to about 30 pounds (related to the type of drug), will not increase indefinitely, after 3 years of drug will be reduced; 4) amenorrhea: with a large impact on menstruation drugs (such as risperidone) in the first six months of about 70% of women will appear, if not change the drug, amenorrhea increasingly heavy, or even irreversible; 5) headache, dizziness and other physical side effects, after 3 months of the drug (6) drug-induced dazed expressions: 3 months to 6 months after the drug is gradually tolerated and disappears, some people need a year; (3) understanding the significance of the time needed to eliminate different clinical manifestations to increase the patience and persistence of family members in treatment, the efficacy of schizophrenia has the right expectations, to avoid choking, do not give children drugs, or use enough drugs, or to drugs like lesbians picking clothes The child misses the best treatment period, and the disease becomes chronic and intractable with repeated attacks. But what makes doctors helpless is that 80% of parents delay 80% of their children in the process of obsessing about the side effects of drugs and being too anxious about the improvement of their condition. This is an important reason for the poor prognosis of 80% of children. IV. Since we see that many parents fail to be patient and persistent in the treatment process and delay the treatment, we have written “Patience, patience, and patience – the time needed to eliminate various clinical manifestations of schizophrenia” and “The effectiveness of schizophrenia, mania, depression, and anxiety disorders”. However, I did not expect that there would be “side effects” and that some parents would overdo it and “patiently” “insist” on inappropriate treatment for as long as a year, which is really This is not my original intention. By “patiently and persistently” I mean “patiently” “persistently” “experienced doctors give the strongest treatment available at home and abroad according to the patient’s symptoms. I mean “patiently” insisting that “an experienced physician gives the strongest and highest dose of the treatment option available at the national and international treatment levels”. However, it is difficult for people outside the circle to judge what an experienced doctor is, because an experienced doctor and a doctor with high title, high education, high title and high social status can sometimes be equated, and sometimes not, and sometimes a doctor is an experienced doctor in this disease but not in another disease, which can lead to errors in judgment of the family.