Diabetic nephropathy is a common complication of diabetes mellitus, manifested as proteinuria, hypertension, edema, anemia, and progressive renal impairment. Diabetic nephropathy requires protein restriction, otherwise the accumulation of protein breakdown products will aggravate renal damage. Low-protein diet is an important tool for non-dialysis treatment of diabetic nephropathy, which can reduce the production and accumulation of protein metabolites and reduce the renal load. From the stage of diabetic nephropathy, for patients with basically normal renal function, protein is 0.8g/Kg per day, for example, for an adult weighing 60Kg, the total daily protein intake is 60Kg*0.8g/Kg=48g; for those with decreased glomerular filtration rate, edema and renal insufficiency, protein is 0.6g/kg. Protein intake below 0.6g/Kg.d is generally not recommended. Long-term administration of very low protein diet may induce hypoproteinemia, malnutrition, etc. Some renal failure patients on a very low protein diet (0.4-0.6g/kg.d) must add essential amino acids or ɑ-keto acids to increase protein synthesis and reduce protein breakdown and metabolite accumulation in the body. In the protein limit range should be as far as possible to choose the essential amino acid-rich high biomass protein, such as dairy, eggs, lean meat (fish, shrimp, poultry, livestock) and other animal proteins. To ensure the efficient use of protein and reduce the production of nitrogenous substances, high value protein should account for more than 50%. An egg can provide 7g of high quality protein, 50g of lean meat and 300ml of dairy can each provide 10g of high quality protein. Rice, white flour and other staple foods due to the lack of certain types of essential amino acids, the vegetable protein contained is incomplete protein, need to be controlled at less than 50%. The protein content of staple foods is about 7-12%, that is, 100 grams of staple foods contain 7-12 grams of vegetable protein, if 300 grams of staple foods are consumed a day, the intake of vegetable protein is 21-36 grams. In order to reduce the intake of vegetable protein, you can choose potatoes, lotus root flour, starch, vermicelli, etc. with lower protein content to replace some of the staple foods. Soy protein is a high-quality protein and does not need to be excessively restricted. Although high quality protein is good, it should not be exceeded. The more good food can not meet all the nutritional needs of the human body, we must reasonably match all kinds of food. 2 or more kinds of food mixed, amino acids can complement each other, such as mixed noodles. The more types of food you combine, the better, and the more distant the species, the better, to be consumed at the same time to be fully utilized by the body.