Generally, Williams syndrome cannot be detected during a routine labor and delivery test, but it may be detectable if an amniocentesis is performed. Williams syndrome is a developmental system disorder that involves multiple organs and is the result of a chromosomal deletion that has a very low prevalence and a low cure rate. Williams syndrome includes mild or moderate mental retardation, resulting in learning difficulties, a unique personality, a peculiar facial appearance, and is accompanied by cardiovascular malformations. There is no specific treatment for this disorder so far, only early intervention such as comprehensive management of speech, physical, occupational, and eating. If there are abnormalities in the heart, then timely treatment is needed, and if necessary, surgical procedures are required, and usually more calcium and vitamin D intake to assist in the treatment. After the birth of the child or obstetric examination found abnormalities, then it is recommended to promptly seek medical attention.