Growth hormone deficiency in children belongs to the category of “renal essence deficiency” syndrome, which can be treated with Chinese medicine. 1. Definition: Kidney essence deficiency refers to the deficiency of kidney essence, brain, bone and marrow failure, with growth retardation, low fertility function and premature aging of adults as the main manifestations of the syndrome. 2. Symptoms and manifestations: delayed development of children, short stature, delayed closure of fontanel, impotence and weakness of bones, mental retardation, pale tongue, white moss, weak pulse. 3. Etiology and pathogenesis: mostly due to the lack of innate endowment (congenital constitution and poor function), or acquired failure to regulate, prolonged illness injury to the kidneys, or overwork, depletion of kidney essence. 4. Treatment: The representative formula commonly used in clinical practice for treating insufficiency of kidney essence is Zuo Gui Wan, which consists of Radix Rehmanniae Praeparata, Rhizoma Dioscoreae, Cornu Cervi Pantotrichum, Fructus Lycii, Semen Cuscutae, Fructus Cuscutae, Radix Angelicae Sinensis, Radix Angelicae Sinensis and Radix Angelicae Sinensis. The main effects are to nourish the liver and kidney, fill in the marrow (replenish the body’s essence and promote bone marrow development). Depending on the patient’s individual constitution and condition, the specific prescription needs to be flexibly added or subtracted according to the TCM doctor’s diagnosis and treatment, and it is important not to blindly use the medication on an individual basis.