AIDS patients can do anal fistula surgery. Anal fistula is mostly caused by perianal abscess, the formation of granulomatous inflammatory hyperplasia-like lesions, the main symptoms manifested in the external mouth of the anal fistula continued to flow pus and blood secretion, at the same time touching the fistula around the anal fistula can also be fluctuating sensation. If the diagnosis is anal fistula, surgical treatment is the main treatment method. Therefore, AIDS patients can do anal fistula surgery. However, because AIDS belongs to the body’s immune function deficiency disease, has a certain degree of contagious. So both during the surgery and after the surgery, should pay attention to prevent infection. Especially health care workers do a good job of protection throughout the operation, after the operation of all the items and instruments in the relevant operation to do special sterilization treatment. After anal fistula surgery for AIDS patients, such as keeping the perianal skin clean and dry, and following the doctor’s orders to change the medicine regularly. At the same time in life should avoid sedentary, diet to light, easy to digest fluid diet.