So far, the exact cause of laryngeal cancer is still unclear, and it may be caused by a combination of factors, mainly related to the following factors: 1, smoking, smoking can cause respiratory tumors. It has been confirmed that benzo(a)pyrene in tobacco tar produced by burning tobacco has carcinogenic effect. Tobacco can also cause mucosal congestion, edema, epithelial hyperplasia and squamous metaplasia, cilia movement stop or retardation, and become the basis of carcinogenesis. The risk of laryngeal cancer is 1.5-4.4 times higher for drinkers than for non-drinkers, and the risk of laryngeal cancer is significantly higher for heavy smokers and drinkers, both of which have synergistic effects. 3.Air pollution, long-term inhalation of productive dust and or gas, such as sulfur dioxide, can lead to respiratory tumors. 4.Occupational factors, long-term exposure to asbestos may lead to laryngeal cancer. 5.Viral infection, EBV and nasopharyngeal cancer are related, which has caused consensus. 6.Sex hormones and receptors, there are significantly more men than women with laryngeal cancer. Excess or lack of certain trace elements will change the structure and function of enzymes, affect cell division and value-added, and lead to genetic mutation. 8.Radiation, squamous cell carcinoma of larynx, fibrosarcoma and adenocarcinoma caused by radiotherapy has been found. 9.Activation of oncogene and inactivation of anti-oncogene. Although the cause of laryngeal cancer is still unclear, the occurrence of laryngeal cancer can be prevented and treated at an early stage by maintaining good living and eating habits, proper exercise, and early consultation when there are symptoms.