It is possible to have intercourse after taking leuprolide, and the use of leuprolide does not affect sexual life. Leuprolide is a gonadotropin drug that is commonly used in clinical practice to treat dysmenorrhea caused by endometriosis or adenomyosis, or to treat excessive menstrual flow with uterine fibroids, as well as to treat breast cancer and precocious puberty. Some people are not suitable for leuprolide, such as pregnant or breastfeeding women, patients with unexplained vaginal bleeding, patients with diabetes mellitus, poor cardiac function or history of cardiovascular disease, or blood clots. Side effects of leuprolide include gastrointestinal reactions such as nausea, vomiting, loss of appetite, loss of libido after leuprolide use, but not inability to have intercourse, and in some patients, decreased vaginal discharge and breast fullness after leuprolide use.