Platelet aggregation is one of the main functions of platelets, which are the smallest blood cells in the blood, accounting for 0.3% of the blood, and are one of the important components of blood. It maintains the integrity of the capillary wall in addition to accelerating clotting function. Malignant tumors enhance platelet aggregation. So how is enhanced platelet aggregation diagnosed? The following is a brief explanation. How to diagnose enhanced platelet aggregation The role of platelets in tumor proliferation and metastasis is mainly manifested as follows: tumor cell-induced platelet aggregation can greatly promote the generation of cancer thrombus, thus making tumor cells easily stay in capillaries due to mechanical resistance; platelets release substances that can induce endothelial cell contraction and expose the subendothelial stromal membrane, facilitating cell adsorption to the stromal membrane as well as cell invasion from blood into tissues; Platelets can promote the cloning and growth of tumor cells at the site of metastasis by releasing platelet-derived growth factors; platelet-derived growth factors and transforming growth factor beta released from activated platelets; and directly stimulate DNA synthesis and mitosis of tumor cells. Therefore, the enhanced platelet aggregation function caused by malignant tumor leads to the hypercoagulable state of blood, which is also one of the important conditions and factors for cancer metastasis and recurrence. For the diagnosis of malignant tumor, the laboratory is based on cytological examination, although its specificity is high. The use of pH, CEA, ferritin, GGT, LDH and other indicators in the detection of chest and abdominal fluid and serum has played a good role in identifying malignant tumor and improving the positive rate.