Loss of appetite may be the result of a variety of factors such as toxin accumulation, marked acidosis, and gastrointestinal mucosal edema, and may be a gastrointestinal symptom of uremia. Therefore when loss of appetite and some other symptoms appear, be fully alert and go to the hospital for examination in time. Many people think that having urine must not be uremia, that is the misunderstanding people have about uremia. Patients have urine, it only means that the removal of water is still possible, but due to kidney disease there is no way to remove toxins. Therefore, these urine are in quantity without quality, which can not play the role of eliminating toxins. Kidney disease is known as the “silent killer” because of the lack of obvious symptoms, insidious onset, low awareness rate, but high disability rate, because there are no specific symptoms, if you do not have regular medical checkups, some problems are difficult to detect in the early stage, once it reaches the end stage, you can only choose kidney replacement. Doctors give patients with kidney disease and their families some advice: regular medical checkups, pay attention to blood pressure, anemia, itching, stomach and other conditions, not headaches, but to dig deeper causes.