Hard pimples on the face may be related to conditions such as acne, acne tumors, folliculitis, boils, etc. Ways of eliminating them include life modification, medication, physical therapy, and surgery. 1. Acne: If acne is more serious, it may lead to hard, red, swollen and painful acne. It can be treated by applying medications such as retinoic acid ointment, benzoyl peroxide gel, fusidic acid, etc., together with oral isotretinoin treatment. It can also be treated by physical methods such as red and blue light irradiation. 2. Acne tumors: sebaceous cysts. If the sebaceous gland ducts are blocked and sebum is not excreted properly, it will form a raised hard lump. It needs to be treated by excision. 3. Folliculitis: It is related to bacterial or fungal infection, which causes inflammation of hair follicles and a red, swollen and painful sensation. It can be treated by applying antibiotic drugs such as clindamycin ointment and fusidic acid cream or by applying antifungal drugs such as sertaconazole nitrate. 4. Boils: Related to Staphylococcus aureus infection, they will present as raised hard pimples with a painful sensation. It can be treated by applying ichthyol ointment, and in severe cases, incision and drainage are needed. Due to the many causes of the disease, patients need to consult a doctor in time for a clear diagnosis and symptomatic treatment. Drugs need to be used in accordance with medical advice.