Pyrazinamide works as an anti-tuberculosis bacillus, with side effects such as arthralgia, loss of appetite, and fever, and the medication should be administered under the supervision of a physician. Pyrazinamide is an anti-tuberculosis mycobacteria drug with strong bactericidal effect on tuberculosis bacilli in macrophages in an acidic environment, and is usually combined with isoniazid and rifampicin in the treatment of tuberculosis. The use of the drug may cause arthralgia, loss of appetite, fever, malaise, yellowing of the skin and sclera, chills and other adverse reactions. Pyrazinamide is contraindicated in allergy, used with caution in diabetes mellitus, gout, hepatic decompensation, etc., used with caution in pregnant women, and should not be used in children. Tuberculosis patients need to follow the doctor’s instructions in accordance with the early, regular, the whole process, adequate amount, the principle of combination of anti-tuberculosis treatment. If you need to use this drug, please use it under the guidance of a professional physician and follow the doctor’s instructions.