High total bile acids in pregnant women may be caused by improper diet, intrahepatic cholestasis during pregnancy or liver diseases. It can be relieved by dietary modification, taking anticholic acid medication and adopting antiviral therapy combined with hepatoprotective therapy. 1. Improper diet: high total bile acids in pregnant women may be caused by excessive intake of high-fat and high-protein foods, which should be avoided and foods rich in vitamins and fiber should be increased. 2. Intrahepatic cholestasis during pregnancy: bile acid-lowering medications, such as ursodeoxycholic acid, etc., should be closely observed during the period of fetal cardiac monitoring and regular ultrasound examination; 3. Liver disease: if the pregnant woman has previously suffered from cirrhosis or hepatitis, which may lead to high total bile acids, liver-protecting and liver-protecting treatments (e.g. magnesium isoglycyrrhizinate, compound glycyrrhizin, etc.) and antiviral drugs, such as entecavir and lamivudine, etc., may be considered. Vitamin supplementation as well as energy combinations are also needed. These are just some of the possible causes of high TBC in pregnant women and the corresponding treatments, and the above medications should be evaluated by a doctor and used under his/her supervision. It is recommended that patients with high total bile acids during pregnancy go to the hospital as soon as possible for a thorough checkup and treatment, so as to avoid affecting their own health and the safety of the fetus.