A raised bump on the back of the hand can be associated with boils, warts and tendon cysts, and medication as well as surgery is recommended for improvement. 1. Boils: Boils may cause a raised bump on the back of the hand. For patients who do not have pus in the early stages of the disease, topical ointments such as ichthyol and mupirocin can be used as prescribed by the doctor to help improve the symptoms. If the lesions are recurrent, antibiotic drugs such as ceftazidime and amoxicillin can be taken orally as prescribed by the doctor to promote the rash to subside. 2. common warts: the back of the hand has a raised hard bag may be common warts caused by common warts, common warts patients can choose laser treatment, electrocautery treatment and freezing treatment to remove, help to shed epidermal warts. For patients who are not suitable for physical therapy, you can also follow the doctor’s instructions to use salicylic acid, imiquimod and other drugs, which can help exfoliate, improve the hand symptoms. 3. Tendon sheath cysts: tendon sheath cysts may also cause a raised hard bag on the back of the hand. If mild pain occurs, you can follow the doctor’s instructions to take aspirin, ibuprofen and other non-steroidal anti-inflammatory drugs, which can help relieve pain. If the cyst continues to grow or if the pain is unbearable, the patient needs to be treated with surgical removal. There are many reasons that lead to a raised hard bag on the back of the hand, it is recommended that patients seek medical examination to clarify the cause of the disease and cooperate with the doctor for standardized treatment.