HFMD is an acute infectious disease caused by an enterovirus infection that lasts about one week and affects children from six months to five years of age, presenting with a fever and rash. The typical rash appears in the mouth, palms, soles, buttocks, and inner thighs, and is rice- or mungbean-sized with surrounding erythema, most of which resolves in about 2-4 days without hyperpigmentation or scarring. Children with HFMD may also have a low-grade fever, with most having a temperature of