Colon cancer T4N0M0 belongs to stage II, which is more serious and patients need to pay attention to it in time. Usually colon cancer can be divided into stage 0~IV according to TNM staging, while colon cancer T4N0M0 belongs to stage II, which indicates that the primary tumor invades to the cycle tissues outside the intestinal wall without lymph node metastasis and distant metastasis. As for patients with locally progressive stage II colon cancer, the 5-year survival rate is 50%~78%, which is more serious, after strictly following the medical advice for surgical treatment, chemotherapy and other comprehensive treatments. Therefore, after clear diagnosis, patients need to actively cooperate with doctors to take targeted treatment according to their conditions, so as to prolong the survival time. Patients usually also need to develop good habits, avoid overwork. They also need to maintain a happy mood, do aerobic exercise such as slow walking, and actively regulate their diet, limit the intake of sugar, and avoid stimulating beverages. It is suggested that patients with colon cancer T4N0M0 should carry out relevant treatments strictly under the guidance of doctors and do a good job in daily care, so as to avoid aggravation of the condition.